I'm an independent web and iOS developer based in London
I have never been much of a fan of changing the color schemes in Visual studio, however whilst working on a Ruby on Rails site for a month or so, I came to enjoy using the e editor’s cappuccino scheme.
Loosely based upon Textmate’s Vibrant Ink scheme, I found it hard to adjust to the dark background at first, however after a few days I’d find it hard to go back.
Using Oren Ellenbogen’s dark theme as a base, I ported the cappuccino theme to Visual Studio 2008:
I’d recommend trying a dark theme for a few days if you haven’t before. It’s easier on your eyes if your programming in the evening, especially if you set up a light behind your monitor.
You can download the colour scheme here.